According to a study, a strong immune response protects young children against Covid-19.
According to a new study, young infants are relatively protected from coronavirus because their systems build a strong immune response to it.
Infants have relatively high quantities of antibodies and immune cells that protect against the virus, according to research done by the University of Bristol and Bristol Royal Hospital for Children.
The findings may explain why younger children appear to be protected from the severe effects of Covid-19 at a time in their development when they are most vulnerable, according to the researchers.
The study was led by university and hospital academics and paediatricians, and it was published in Cell Reports Medicine.
This is crucial information for the development of future Covid-19 vaccines that aim to induce and duplicate the protective immunity profile.
The authors of the study wanted to determine why children were only mildly impacted by the virus during the pandemic, especially since younger infants are known to be more susceptible to other respiratory viruses like the flu.
The researchers studied the immune responses of four newborns under three months old who had been diagnosed with Covid at the onset of the pandemic in March 2020, as well as their parents and other adult patients who had recovered from the virus.
The findings, according to Dr. Anu Goenka, a clinical lecturer in paediatric infectious diseases and immunology at the University of Bristol, could contribute in the development of vaccines that match the protection provided by children.
“We have showed what protective immunity looks like in terms of the make-up of particular antibodies and immune cells directed against SARS-CoV-2 by doing a detailed investigation on young children who are relatively protected from severe Covid-19,” he said.
“This is critical information for the development of future Covid-19 vaccines that aim to induce and duplicate the protective immune signature.”
The researchers now seek to validate these findings in a larger cohort of newborns, as well as comparing the immune responses of newborns and adults during and after infection.